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89 The effectivity of the HAbased hydrogel could be further enhanced and used as a carrier to locally administer other novel drugs for CDLBP treatment

GLP-1 receptor activation sends signals of fullness to the brain, slows the rate at which food leaves the stomach, and supports more stable post-meal blood sugar responses

One such example is compounded semaglutide, which may be an option during a drug shortage

this mechanism contributes to lower postprandial blood glucose

All experimental techniques followed the guidelines for the Care and Use of Laboratory Animals and were conducted in compliance with the ARRIVE guidelines.37 The Ethics Committee of Animal Experiments of Binzhou Medical University Hospital approved all animal experimental protocols (ethical approval number: 2022101422)